STEVENS-JOHNSON SYNDROME COMPLICATED BY OBSTRUCTIVE UROPATHY, PNEUMOTHORAX, AND PNEUMOMEDIASTINUM: A CASE REPORT AND LITERATURE REVIEW

Stevens-Johnson Syndrome complicated by obstructive uropathy, pneumothorax, and pneumomediastinum: a case report and literature review

Abstract Background Stevens-Johnson Syndrome (SJS) is an acute mucocutaneous eruption with blisters of the skin and haemorrhagic erosions of mucous membranes.This report describes air-leak syndrome and obstructive uropathy occurring simultaneously in a teenage patient affected by SJS.Case presentation A 17-year-old Malay female with SJS suffered fr

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Functional conservation of Asxl2, a murine homolog for the Drosophila enhancer of trithorax and polycomb group gene Asx.

BackgroundPolycomb-group (PcG) and trithorax-group (trxG) proteins regulate histone methylation to establish repressive and active chromatin configurations at target loci, respectively.These chromatin configurations are passed on from mother to daughter cells, thereby causing heritable changes in gene expression.The activities of PcG and trxG prote

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